GSK

GSK is a UK pharmaceutical company that develops, makes and sells medicines and vaccines. It reports three product groups. Specialty Medicines, about 44% of sales in Q3 2026, includes HIV medicines from its ViiV Healthcare unit, respiratory and immunology medicines, and cancer medicines. Vaccines, about 29% of sales, includes Shingrix for shingles, meningitis vaccines and Arexvy for RSV.

General Medicines, about 27% of sales, includes inhaled medicines such as Trelegy and older medicines whose sales fall over time. Sales were £8.9 billion in Q3 2026. GSK earns most of its profit from patented medicines, so it must replace medicines that lose patent protection with new ones from its research or from acquisitions. Its main HIV medicine, dolutegravir, loses exclusivity from 2028 to 2030.

GSK trades at a discount because the market doubts that its new medicines can replace the HIV sales it will lose when dolutegravir patents expire from 2028 to 2030. General Medicines sales also fall, by 9% in Q2 2026, and a late-stage failure in July 2026 added to the doubt: GSK stopped camlipixant for chronic cough and took a £1.3 billion impairment. US drug-price pressure is a second concern, although GSK's December 2025 agreement with the US government gives it relief from Section 232 tariffs through January 20, 2029. GSK now buys growth with debt: net debt rose to £20.7 billion at September 30, 2026, after it bought Nuvalent for about $10.6 billion in July 2026.

It also plans 22 phase III trial starts in 2026. For the gap to close, GSK must win approvals and fast launches for its new medicines, keep its 2026 guidance of 7% to 9% core EPS growth, stay on track for its target of more than £40 billion of sales in 2031, and keep its operating margin stable through the dolutegravir patent expiry. Two tests passed in October 2026. The FDA approved Hibsago (bepirovirsen) for chronic hepatitis B on October 20, 2026, and GSK kept its 2026 guidance in the Q3 2026 report on October 28, 2026.

But core EPS grew only 1% in Q3 2026, because R&D and interest costs rose, and GSK expects 2026 growth in the lower half of its range. The next tests are the FDA decision on neladalkib for lung cancer, with a target date of November 27, 2026, and the full-year 2026 report with 2027 guidance, expected on February 3, 2027. The gap can close only over several years, as new launches grow before and through 2028 to 2030. The main risk is that new medicines grow too slowly to replace HIV sales.

1. Oct 26, 2026Passed

   FDA decision on bepirovirsen for chronic hepatitis BUS approval by October 26, 2026 passes; a rejection or a delay fails.Outcome: The FDA approved Hibsago (bepirovirsen) on October 20, 2026, before the target date.
2. Oct 28, 2026Passed

   Q3 2026 results and Nuvalent accountingCore EPS growth in line with 7% to 9% for 2026 and growth in Specialty Medicines at a low double-digit rate pass; a guidance cut or a further pipeline impairment fails.Outcome: GSK kept its 2026 core EPS growth guidance of 7% to 9%, Specialty Medicines grew 15% and there was no significant impairment, although core EPS grew only 1% in the quarter.
3. Nov 27, 2026Pending

   FDA decision on neladalkib for ALK-positive lung cancerApproval by the November 27, 2026 target date passes; a rejection or a delay fails.
4. Feb 3, 2027 · est.Pending

   Full-year 2026 results and 2027 guidance2027 guidance with sales and core profit growth and a stable margin outlook through the dolutegravir patent expiry passes; lower guidance fails.

Every passed and failed checkpoint across all picks

• October 28, 2026GSK reported Q3 2026 results. Sales were £8.9 billion, up 5% at constant exchange rates. Specialty Medicines grew 15%, Vaccines fell 2%, and General Medicines were stable. Core operating profit grew 5%, but core EPS grew only 1%, because of higher R&D spending and higher interest costs after the Nuvalent purchase. Total operating profit fell 16%, mainly because of £328 million of restructuring charges. GSK kept its 2026 guidance of 3% to 5% sales growth and 7% to 9% core EPS growth, with core EPS growth in the lower half of that range. Net debt was £20.7 billion at September 30, 2026.
• October 26, 2026GSK's licensor Hansoh Pharma reported a second positive phase III trial of Ris-Rez in China. In relapsed osteosarcoma, Ris-Rez lowered the risk of disease progression or death by 67% against chemotherapy. At the same ESMO congress, GSK also showed positive early data for Ris-Rez in small cell lung cancer and for Mo-Rez in ovarian cancer.
• October 20, 2026The FDA approved Hibsago (bepirovirsen) for chronic hepatitis B, with standard antiviral treatment, in adults without cirrhosis whose virus is suppressed and whose HBsAg level is 3,000 IU/ml or lower. The FDA gave the approval under priority review, before the October 26, 2026 target date. Treatment lasts six months.

Last earnings

October 28, 2026

Next earnings

Expected about February 3, 2027. The company has not confirmed the date.

• 20-FAnnual report for the period ended Dec 31, 2025Filed March 6, 2026 · gsk-20251231
• 20-FAnnual report for the period ended Dec 31, 2024Filed March 3, 2025 · gsk-20241231

Every filing on SEC EDGAR (CIK 1131399)

• Dolutegravir, GSK's main HIV medicine, loses exclusivity from 2028 to 2030. HIV sales were £2.1 billion in Q3 2026, about a quarter of group sales. If new HIV medicines and other launches do not grow fast enough, sales and margins fall in that period.
• New medicines can fail late in development. In July 2026, camlipixant failed to show enough benefit in phase III, and GSK took a £1.3 billion impairment. GSK plans 22 phase III trial starts in 2026, with 18 started by October 28, 2026, and some of them will fail.
• US drug prices are under political pressure. GSK agreed with the US government in December 2025 to lower some prices in exchange for relief from Section 232 tariffs through January 20, 2029, and GSK and ViiV joined the Generous Model of the Centers for Medicare and Medicaid Services from June 15, 2026. More US price rules can lower sales.
• Debt rises with acquisitions. Net debt was £20.7 billion at September 30, 2026, up from £14.5 billion at December 31, 2025, mainly because of the Nuvalent, RAPT and 35Pharma purchases. GSK funded Nuvalent mainly with debt. GSK expects interest charges of about £700 million to £750 million in 2026.
• Zantac lawsuits continue. The Delaware Superior Court granted summary judgment for the remaining cases filed on or before December 1, 2025, on April 13, 2026, and an appeal of about 14,000 dismissed federal cases waits for a decision expected in the second half of 2026.

GSK had £23.70 billion of borrowings at September 30, 2026, including lease liabilities: £21.70 billion long-term and £2.00 billion short-term. Cash and liquid investments were £2.96 billion, so net debt was £20.74 billion, up from £14.45 billion at December 31, 2025. Read more

Yield at the current rate

3.6% (current annual rate, at today’s price)

Dividend yield

3.6% (last 12 months, at today’s price of $50.60)

Paid per share

$1.816 in the last 12 months (4 payments)

Current annual rate

$1.808 ($0.452 × 4 a year)

Latest ex-dividend date

August 14, 2026, $0.452 per share

Dividends per share by year

From 2020 to 2025, the dividend fell by about 4.0% a year. From 2015 to 2025, the dividend fell by about 3.7% a year.

Source: company filings and market data, read on November 13, 2026. The ex-dividend date is the first day a buyer no longer gets the next payment.